Radiesse in Harley Street
Collagen-stimulating injectable treatment in Central London
Key facts
Radiesse is one of the most powerful biostimulators for your skin. It is an advanced injectable treatment designed to restore facial structure, improve skin quality, and stimulate natural collagen production.
How it works: calcium hydroxyapatite microspheres stimulate collagen and elastin production
Treatment time: 30-45 minutes
Anaesthesia: topical numbing cream
Recovery time: none
Results: immediate improvement with progressive collagen stimulation over several months
Lasts: approximately 2 years depending on treatment area and technique
What is Radiesse?
Radiesse is a biostimulatory injectable treatment composed of calcium hydroxyapatite (CaHA) microspheres suspended in a soft gel carrier. Unlike traditional fillers that only add temporary volume, Radiesse also stimulates the body’s own collagen production, helping improve skin structure, firmness, and elasticity over time.
Radiesse is widely used in facial rejuvenation to restore lost volume, improve jawline definition, soften deeper folds, and enhance facial contours while maintaining a natural appearance.
At Dr Gino Vissers in Harley Street, Radiesse treatments are carefully tailored to each patient’s anatomy and aesthetic goals. Dr. Gino Vissers focuses on elegant, subtle rejuvenation that restores youthful structure without creating an overfilled or artificial appearance.
How does Radiesse work?
Radiesse works through a dual mechanism. Initially, the gel carrier provides immediate support and structural improvement to the treated area. Over time, the calcium hydroxyapatite particles stimulate fibroblasts within the skin to produce new collagen and elastin.
As the gel component gradually dissolves, the newly stimulated collagen helps maintain skin firmness and support for many months afterwards. This makes Radiesse particularly attractive for patients seeking longer-lasting and regenerative aesthetic treatments rather than temporary filling alone.
Modern regenerative aesthetic medicine increasingly focuses on collagen stimulation and tissue quality improvement rather than simply adding volume.
Neat Radiesse vs Hyperdiluted Radiesse: What's the difference?
At Dr Gino Vissers in Harley Street, both neat and hyperdiluted Radiesse treatments are tailored carefully to the patient’s anatomy, skin quality, and aesthetic goals. Neat Radiesse is typically used for structural facial rejuvenation and contouring, whereas hyperdiluted Radiesse is often chosen to improve skin texture, elasticity, and crepey skin through collagen stimulation.
| Neat Radiesse | Hyperdiluted Radiesse | |
|---|---|---|
| Main purpose | Structural support and facial contouring | Skin rejuvenation and collagen stimulatio |
| Dilution | Undiluted | Mixed with saline |
| Volume enhancement | Significant | Minimal to none |
| Collagen stimulation | Yes | Yes |
| Best treatment areas | Jawline, chin, cheeks, pre-jowl area | Neck, décolletage, lower face, hands, abdomen, knees |
| Ideal patient | Patients with volume loss or loss of facial definition | Patients with crepey skin, mild laxity, or skin thinning |
| Results onset | Immediate contour improvement plus gradual collagen production | Gradual improvement over weeks to months |
Am I suitable for Radiesse?
Radiesse may be suitable for patients who wish to improve facial structure, restore volume loss, or stimulate collagen production without surgery.
You may be a suitable candidate if you are concerned about:
- Early facial ageing
- Loss of jawline definition
- Mild skin laxity
- Crepey skin in the décolletage area
- Loss of collagen and elasticity
- Hollowing or contour deficiencies
- Ageing hands
During your consultation, Dr. Gino Vissers will assess your facial anatomy, skin quality, and aesthetic goals to determine whether Radiesse or alternative treatments may be most appropriate for you.

What happens during Radiesse treatment?
Your Radiesse treatment will consist of the following steps:
1. Consultation: During your consultation with Dr. Gino Vissers, your specific concerns and goals will be assessed. The areas to be treated will be identified, and a personalised treatment plan will be developed.
2. Preparation: Prior to the procedure, the target area will be cleansed, and a topical numbing cream or local anaesthetic may be applied to ensure your comfort during the injections.
3. Injection: Dr. Gino Vissers will carefully inject Radiesse into the predetermined areas. Profhilo will be injected using needles or cannulas. Most patients tolerate treatment very well. Mild swelling, redness, tenderness, or bruising can occur afterwards but usually settle within several days.
4. Quick recovery:
Patients return to their activities immediately after treatment, although strenuous exercise and excessive heat exposure should be avoided for approximately 24–48 hours.
Are there any precautions I should be aware of?
Prior to undergoing a Radiesse treatment, it's essential to follow specific instructions and be aware of important precautions. Here are some key considerations:
- Pregnancy and Breastfeeding: It is generally recommended to avoid Radiesse during pregnancy or while breastfeeding, as the potential effects on the foetus or infant are not fully understood.
- Avoid Aspirin and Alcohol: To reduce the likelihood of bruising, it's advisable to avoid consuming aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), and alcohol from a few days before your treatment until 24 hours after your treatment.
- Quiet Recovery: allow yourself some quiet time in the first 24 hours after your treatment. Avoid excessive heat (including sauna), intense exercise, and facial massages as these may increase infection risks.
Recovery and results after Radiesse
You can resume normal activities, drive home, or return to work immediately after the treatment. After your treatment, you may experience some mild swelling. Avoid any heavy excercise, sauna, facial massages or alcohol in the first 24-48 hours following your treatment.
Results from Radiesse occur in two phases:
- Immediately after treatment, patients often notice improved structure, contour, and support from the gel component of the product. Over the following weeks and months, collagen stimulation gradually improves skin firmness, elasticity, and quality.
- The regenerative effects of diluted and hyperdiluted Radiesse typically continue developing progressively for several months after treatment.




